• Ageing is a continuous ongoing dynamic chronological process.
  • It is genetically controlled and inevitable.
  • Senescence of the skin, particularly that of the face, is a result of various factors that may be genetically determined natural slowing process of the body or originating from the external environmental assaults.
  • These extrinsic factor such as UV radiation (most important), gravity temperature variations, wind humidity chemical pollutants and irritants depleted ozone layer, poor nutrition, physical and mental stress and social habits (eg. smoking).
  • Wrinkles are the earliest and cosmetically most unwanted problem.