Velvety Neck/ Velvety Skin Folds/ Acanthosis Nigricans

  • Acanthosis nigricans (AN) is characterized by hyper-pigmented verrucous or velvety plaques that usually appear on flexural surfaces and in intertriginous regions.
  • It is most commonly seen in individuals with insulin resistance sates especially obesity and less frequently with other metabolic diseases, genetic syndromes, drugs, and malignancy.